| Product Name | Anti-Phospho-Daxx (Ser668) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser668 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DAXX |
|---|---|
| Gene Synonyms | DAP6 EAP1 BING2 |
| Gene Full Name | death domain associated protein |
| Gene Summary | This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008] |
| Alternative Names | antibody BING 2 BING2 CENP-C binding protein DAP 6 DAP6 Daxx DAXX_HUMAN Death associated protein 6 Death domain associated protein 6 Death domain associated protein Death domain-associated protein 6 EAP 1 EAP1 ETS1 associated protein 1 ETS1-associated protein 1 Fas binding protein Fas death domain associated protein Fas death domain-associated protein hDaxx MGC126245 MGC126246 |
| Molecular Weight(MW) | 81 kDa |
| Cellular Localization | Centromere,Chromosome,Cytoplasm,Nucleus. |
| SwissProt ID | Q9UER7 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
