| Gene Symbol |
DNM1L
|
| Gene Synonyms |
DLP1 DRP1 DVLP EMPF OPA5 EMPF1 DYMPLE HDYNIV |
| Gene Full Name |
dynamin 1L |
| Gene Summary |
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] |
| Alternative Names |
DLP1 dnm1l DNM1L_HUMAN Dnm1p/Vps1p-like protein dnml1 DRP1 DVLP Dymple Dynamin 1 like Dynamin family member proline-rich carboxyl-terminal domain less Dynamin like protein Dynamin related protein 1 Dynamin-1-like protein Dynamin-like protein 4 Dynamin-like protein Dynamin-like protein IV Dynamin-related protein 1 DYNIV 11 EMPF EMPF1 FLJ41912 HdynIV VPS1 |
| Molecular Weight(MW) |
82 kDa |
| Cellular Localization |
Coated pit,Cytoplasm,Cytoplasmic vesicle,Golgi apparatus,Membrane,Mitochondrion,Mitochondrion outer membrane,Peroxisome,Synapse. |