| Product Name | Anti-Phospho-Lck (Tyr192) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr192 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LCK |
|---|---|
| Gene Synonyms | LSK YT16 IMD22 p56lck pp58lck |
| Gene Full Name | LCK proto-oncogene, Src family tyrosine kinase |
| Gene Summary | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016] |
| Alternative Names | IMD22 LCK Lck p56 LCK proto-oncogene Src family tyrosine kinase LCK_HUMAN Leukocyte C-terminal Src kinase LSK Lymphocyte cell specific protein tyrosine kinase Lymphocyte cell-specific protein-tyrosine kinase Lymphocyte specific protein tyrosine kinase Membrane associated protein tyrosine kinase Oncogene lck P56 LCK p56(LSTRA) protein tyrosine kinase p56-LCK p56lck pp58 lck pp58lck Protein YT16 Proto oncogene tyrosine protein kinase LCK Proto-oncogene Lck Protooncogene tyrosine protein kinase LCK T cell specific protein tyrosine kinase T cell-specific protein-tyrosine kinase T lymphocyte specific protein tyrosine kinase p56lck Tyrosine-protein kinase Lck YT 16 YT16 |
| Molecular Weight(MW) | 58 kDa |
| Cellular Localization | Cell membrane,Cytoplasm,Membrane. |
| SwissProt ID | P06239 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
