| Gene Symbol |
BCL11A
|
| Gene Synonyms |
EVI9 CTIP1 DILOS ZNF856 HBFQTL5 SMARCM1 |
| Gene Full Name |
BCL11 transcription factor A |
| Gene Summary |
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names |
2810047E18Rik B cell CLL/lymphoma 11A (zinc finger protein) B cell CLL/lymphoma 11A (zinc finger protein) isoform 2 B-cell CLL/lymphoma 11A B-cell lymphoma/leukemia 11A BC11A_HUMAN BCL-11A BCL11A BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1 BCL11A L BCL11A S BCL11A XL BCL11a-M BCL11AL BCL11AS BCL11AXL C2H2 type zinc finger protein COUP TF interacting protein 1 COUP-TF-interacting protein 1 CTIP1 CTIP1 mouse homolog of D930021L15Rik Ecotropic viral integration site 9 Ecotropic viral integration site 9 homolog Ecotropic viral integration site 9 protein Ecotropic viral integration site 9 protein homolog EVI-9 Evi9 Evi9 mouse homolog of FLJ10173 FLJ34997 HBFQTL5 KIAA1809 mKIAA1809 OTTHUMP00000159788 OTTHUMP00000159789 OTTHUMP00000201250 OTTHUMP00000202084 Zinc finger protein 856 ZNF856 |
| Molecular Weight(MW) |
91 kDa |
| Cellular Localization |
Chromosome,Cytoplasm,Nucleus. |