| Gene Symbol |
VIM
|
| Gene Full Name |
vimentin |
| Gene Summary |
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017] |
| Alternative Names |
CTRCT30 Epididymis luminal protein 113 FLJ36605 HEL113 VIM VIME_HUMAN Vimentin |
| Molecular Weight(MW) |
54 kDa |
| Cellular Localization |
Cell membrane,Cell projection,Cytoplasm,Cytoskeleton,Intermediate filament,Membrane,Nucleus. |