| Product Name | Anti-Phospho-UBF1 (Thr117) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Thr117 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | UBTF |
|---|---|
| Gene Synonyms | UBF UBF1 UBF2 UBF-1 CONDBA NOR-90 |
| Gene Full Name | upstream binding transcription factor |
| Gene Summary | This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011] |
| Alternative Names | 90 kDa nucleolus organizer region autoantigen Autoantigen NOR-90 NOR 90 Nucleolar transcription factor 1 UBF 1 UBF UBF-1 UBF1_HUMAN Ubtf Upstream binding factor 1 upstream binding transcription factor RNA polymerase I Upstream-binding factor 1 |
| Molecular Weight(MW) | 89 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | P17480 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
