| Product Name | Anti-Phospho-VEGFR1 (Tyr1048) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Tyr1048 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FLT1 |
|---|---|
| Gene Synonyms | FLT FLT-1 VEGFR1 VEGFR-1 |
| Gene Full Name | fms related receptor tyrosine kinase 1 |
| Gene Summary | This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009] |
| Alternative Names | EC 2.7.10.1 FLT 1 FLT Flt-1 FLT1 Fms like tyrosine kinase 1 Fms related tyrosine kinase 1 Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor Fms-like tyrosine kinase 1 FRT Soluble VEGF receptor 1 14 Soluble VEGFR1 variant 2 Soluble VEGFR1 variant 21 Tyrosine protein kinase FRT Tyrosine protein kinase receptor FLT Tyrosine-protein kinase FRT Tyrosine-protein kinase receptor FLT Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor vascular permeability factor receptor Vascular permeability factor receptor 1 Vascular permeability factor receptor VEGFR 1 VEGFR-1 VEGFR1 VGFR1_HUMAN |
| Molecular Weight(MW) | 151 kDa |
| Cellular Localization | Cell membrane,Cytoplasm,Endosome,Membrane,Secreted. |
| SwissProt ID | P17948 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
