| Product Name | Anti-Phospho-MCM3 (Ser160) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser160 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MCM3 |
|---|---|
| Gene Synonyms | HCC5 P1.h RLFB P1-MCM3 |
| Gene Full Name | minichromosome maintenance complex component 3 |
| Gene Summary | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018] |
| Alternative Names | Cervical cancer proto oncogene 5 DNA polymerase alpha holoenzyme associated P1 DNA polymerase alpha holoenzyme associated protein P1 DNA polymerase alpha holoenzyme-associated protein P1 DNA replication factor MCM3 DNA replication licensing factor mcm3 HCC 5 HCC5 hRlf beta subunit Human cervical cancer proto oncogene 5 MCM 3 mcm3 MCM3 minichromosome maintenance deficient 3 MCM3_HUMAN MGC1157 Minichromosome maintenance complex component 3 Minichromosome maintenance deficient 3 Minichromosome maintenance protein 3 P1 h P1 MCM3 P1 Protein P1-MCM3 P1.h p102 P102 protein Replication licensing factor beta subunit RLF beta subunit RLF subunit beta RLFB |
| Molecular Weight(MW) | 91 kDa |
| Cellular Localization | Chromosome,Nucleus. |
| SwissProt ID | P25205 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
