| Gene Symbol |
ZEB1
|
| Gene Synonyms |
BZP TCF8 AREB6 FECD6 NIL2A PPCD3 ZFHEP ZFHX1A DELTAEF1 |
| Gene Full Name |
zinc finger E-box binding homeobox 1 |
| Gene Summary |
This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010] |
| Alternative Names |
AREB 6 BZP Delta crystallin enhancer binding factor 1 DELTA EF1 FECD6 MGC133261 Negative regulator of IL 2 Negative regulator of IL2 NIL 2 A NIL 2 A zinc finger protein NIL 2A NIL-2-A zinc finger protein NIL2A Posterior polymorphous corneal dystrophy 3 PPCD3 Represses interleukin 2 expression TCF 8 TCF-8 TCF8 Transcription factor 8 (represses interleukin 2 expression) Transcription factor 8 ZEB 1 ZEB ZEB1 ZEB1_HUMAN ZFHEP ZFHX 1A ZFHX1A Zinc finger E box binding homeobox 1 Zinc finger E-box-binding homeobox 1 Zinc finger homeodomain enhancer binding protein |
| Molecular Weight(MW) |
124 kDa |
| Cellular Localization |
Nucleus. |