| Gene Symbol |
IFNAR1
|
| Gene Synonyms |
AVP IFRC IFNAR IFNBR CRF2-1 IMD106 IFN-R-1 IFN-alpha-REC |
| Gene Full Name |
interferon alpha and beta receptor subunit 1 |
| Gene Summary |
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020] |
| Alternative Names |
Alpha type antiviral protein Antiviral protein alpha-type Antiviral protein beta-type AVP Beta type antiviral protein CRF2-1 Cytokine receptor class-II member 1 Cytokine receptor family 2 member 1 IFN alpha REC IFN alpha receptor IFN alpha/beta Receptor alpha IFN beta receptor IFN Interferon-beta receptor IFN-alpha/beta receptor 1 IFN-R-1 IFNAR Ifnar1 IFNBR IFRC INAR1_HUMAN Interferon (alpha beta and omega) receptor 1 interferon alpha and beta receptor subunit 1 Interferon alpha/beta receptor 1 Interferon alpha/beta receptor alpha chain Interferon beta receptor 1 interferon receptor 1 Interferon-alpha receptor Type I interferon receptor 1 |
| Molecular Weight(MW) |
64 kDa |
| Cellular Localization |
Cell membrane, Late endosome, Lysosome. |