| Gene Symbol |
PRKCQ
|
| Gene Synonyms |
PRKCT nPKC-theta |
| Gene Full Name |
protein kinase C theta |
| Gene Summary |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008] |
| Alternative Names |
KPCT_HUMAN MGC126514 MGC141919 nPKC theta nPKC-theta nPKCtheta OTTHUMP00000043364 OTTHUMP00000043365 PKC 0 PKC0 Prkcq PRKCT Protein kinase C theta Protein kinase C theta type Protein Kinase Ctheta |
| Molecular Weight(MW) |
82 kDa |
| Cellular Localization |
Cell membrane, Cytoplasm, Membrane. |