| Gene Symbol |
BCL6
|
| Gene Synonyms |
BCL5 LAZ3 BCL6A ZNF51 ZBTB27 |
| Gene Full Name |
BCL6 transcription repressor |
| Gene Summary |
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| Alternative Names |
B cell CLL/lymphoma 6 B cell lymphoma 6 protein B-cell lymphoma 5 protein B-cell lymphoma 6 protein BCL 5 Bcl 6 BCL-5 BCL-6 BCL5 BCL6 BCL6_HUMAN BCL6A cys his2 zinc finger transcription factor LAZ 3 LAZ 3 protein LAZ3 Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3) Lymphoma associated zinc finger gene on chromosome 3 Protein LAZ-3 ZBTB 27 ZBTB27 Zinc finger and BTB domain containing protein 27 Zinc finger and BTB domain-containing protein 27 (ZBTB27) Zinc finger and BTB domain-containing protein 27 Zinc Finger Protein 51 (ZNF51) Zinc finger protein 51 zinc finger transcription factor BCL6S ZNF 51 ZNF51 |
| Molecular Weight(MW) |
79 kDa |
| Cellular Localization |
Nucleus. |