| Gene Symbol |
HGS
|
| Gene Synonyms |
HRS |
| Gene Full Name |
hepatocyte growth factor-regulated tyrosine kinase substrate |
| Gene Summary |
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010] |
| Alternative Names |
Hepatocyte growth factor regulated tyrosine kinase substrate Hepatocyte growth factor-regulated tyrosine kinase substrate HGF-regulated tyrosine kinase substrate HGNC:4897 HGS HGS_HUMAN Hrs Human growth factor regulated tyrosine kinase substrate Protein pp110 ZFYVE8 |
| Molecular Weight(MW) |
86 kDa |
| Cellular Localization |
Cytoplasm, Endosome, Membrane. |