| Product Name | Anti-Phospho-Ras-GRF1 (Ser916) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser916 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RASGRF1 |
|---|---|
| Gene Synonyms | GNRP GRF1 CDC25 GRF55 CDC25L H-GRF55 PP13187 ras-GRF1 |
| Gene Full Name | Ras protein specific guanine nucleotide releasing factor 1 |
| Gene Summary | The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009] |
| Alternative Names | CDC25 CDC25L GNRP GRF1 GRF55 Guanine nucleotide exchange factor Guanine nucleotide releasing factor 55 kD Guanine nucleotide releasing protein guanine nucleotide-releasing factor 1 Guanine nucleotide-releasing protein H GRF55 HGRF55 PP13187 Ras protein specific guanine nucleotide releasing factor 1 Ras specific guanine nucleotide releasing factor Ras specific guanine nucleotide releasing factor CDC25 homolog Ras specific nucleotide exchange factor CDC25 Ras-GRF1 Ras-specific guanine nucleotide-releasing factor 1 Ras-specific nucleotide exchange factor CDC25 RASGRF1 RGRF1_HUMAN |
| Molecular Weight(MW) | 145 kDa |
| Cellular Localization | cytosol, growth cone, neuron projection, plasma membrane. |
| SwissProt ID | Q13972 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
