| Gene Symbol |
IRAK3
|
| Gene Synonyms |
ASRT5 IRAKM |
| Gene Full Name |
interleukin 1 receptor associated kinase 3 |
| Gene Summary |
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| Alternative Names |
ASRT5 IL 1 receptor associated kinase M IL-1 receptor-associated kinase M IL1 receptor associated kinase M Interleukin 1 receptor associated kinase 3 Interleukin 1 receptor associated kinase M Interleukin-1 receptor-associated kinase 3 IRAK M IRAK-3 IRAK-M Irak3 IRAK3_HUMAN |
| Molecular Weight(MW) |
68 kDa |
| Cellular Localization |
Cytoplasm, Nucleus. |