| Product Name | Anti-Phospho-PFKFB2 (Ser483) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser483 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PFKFB2 |
|---|---|
| Gene Synonyms | PFK-2/FBPase-2 |
| Gene Full Name | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| Gene Summary | The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | 6 phosphofructo 2 kinase/ fructose 2 6 bisphosphatase 6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 3 6-bisphosphatase 6-P2ase 3 6-P2ASE brain/placenta-type isozyme 6PF 2 K/Fru 2 6 P2ASE brain/placenta type isozyme 6PF 2-K/Fru 2 6 P2ase 3 6PF-2-K/Fru-2 F263_HUMAN fructose 6 phosphate 2 kinase/fructose 2 6 bisphosphatase Fructose-2 Inducible 6 phosphofructo 2 kinase/fructose 2 6 bisphosphatase iPFK 2 iPFK-2 IPFK2 PFK/FBPase 3 PFK2 PFKFB3 Renal carcinoma antigen NY REN 56 Renal carcinoma antigen NY-REN-56 uPFK 2 |
| Molecular Weight(MW) | 58 kDa |
| Cellular Localization | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase complex, Cytosol, Nucleoplasm. |
| SwissProt ID | O60825 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
