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OM684137
Discount Price
OM684137-100ul
100ul
Product Profile
Product Name Anti-Phospho-TrkA (Tyr496) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Tyr496
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol NTRK1
Gene Synonyms MTC
TRK
TRK1
TRKA
Trk-A
p140-TrkA
Gene Full Name neurotrophic receptor tyrosine kinase 1
Gene Summary This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
Alternative Names gp140trk
High affinity nerve growth factor receptor
High affinity nerve growth factor receptor precursor
MTC
Neurotrophic tyrosine kinase receptor type 1
NTRK1
NTRK1_HUMAN
Oncogene TRK
p14-TrkA
p140 TrkA
p140-TrkA
Slow nerve growth
Trk A
TRK
Trk-A
TRK1
TRK1-transforming tyrosine kinase protein
Tropomyosin-related kinase A
Tyrosine kinase receptor A
Tyrosine kinase receptor
Molecular Weight(MW) 87 kDa
Cellular Localization Cell membrane, Endosome, Membrane.
Database Links
SwissProt ID P04629
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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