ICC/IF
AF488 staining on IF;Sample: MCF7 cellPrimary Ab: 30µg/ml Mouse Anti-Rat INSR AntibodySecond Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody| Product Name | Monoclonal Antibody to Insulin Receptor (INSR) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | RPA895Ra01-Recombinant Insulin Receptor (INSR) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1Kappa |
| Host Species | Mouse |
| Tested Applications | ICC/IF |
| ICC/IF: 5-30µg/mL |
|
| Species Reactivity | Rat |
| Concentration | 1mg/ml |
| Purification | Protein A/G |
| Gene Symbol | INSR |
|---|---|
| Gene Synonyms | HHF5,CD220 |
| Gene Full Name | insulin receptor |
| Gene Summary | This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
| Alternative Names | CD220 ISR HHF5 IR |
ICC/IF
AF488 staining on IF;Sample: MCF7 cellPrimary Ab: 30µg/ml Mouse Anti-Rat INSR AntibodySecond Ab: 2μg/ml AF488-Linked Caprine Anti-Mouse IgG Polyclonal Antibody| Application Notes | ICC/IF: 5-30µg/mL |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
