Monoclonal Antibody to Microtubule Associated Protein RP/EB Family, Member 1 (MAPRE1)
Antibody Type
Primary Antibodies
Immunogen
RPG491Hu01-Recombinant Microtubule Associated Protein RP/EB Family, Member 1 (MAPRE1)
Key Feature
Clonality
Monoclonal
Isotype
IgG1 Kappa
Host Species
Mouse
Tested Applications
WB
WB: 0.01-3µg/mL
Species Reactivity
Human
Concentration
1mg/ml
Purification
Protein A/G
Target Information
Gene Symbol
MAPRE1
Gene Synonyms
EB1
Gene Full Name
microtubule associated protein RP/EB family member 1
Gene Summary
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]
Alternative Names
EB1 Adenomatous Polyposis Coli-Binding protein APC-binding protein EB1 End-binding protein 1
Application
WB
Western Blot,Sample: Lane1: Hela cell lysate,Lane2: Jurkat cell lysate,Lane3: A431 cell lysate Primary Ab: 3µg/ml Mouse Anti-Human MAPRE1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Application Notes
WB: 0.01-3µg/mL
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.