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Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI)

Catalog Number:OM699656
Human
WB
OM699656
Discount Price
OM699656-100ul
100ul
Product Profile
Product Name Monoclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI)
Antibody Type Primary Antibodies
Immunogen EPA394Hu61-Eukaryotic Tissue Factor Pathway Inhibitor (TFPI)
Key Feature
Clonality Monoclonal
Isotype IgG1 Kappa
Host Species Mouse
Tested Applications WB
WB: 0.01-2µg/mL
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A/G
Target Information
Gene Symbol TFPI
Gene Synonyms EPI,TFI,LACI,TFPI1
Gene Full Name tissue factor pathway inhibitor
Gene Summary This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Alternative Names TFI
EPI
LACI
TFPI1
Lipoprotein-Associated Coagulation Inhibitor
Extrinsic pathway inhibitor
Application

WB

Western Blot,Sample: Rat Plasma Primary Ab: 0.3µg/ml Mouse Anti-Human TFPI Antibody Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody

WB

Western Blot,Samples: Lane1: Hela cell lysate,Lane2: HepG2 cell lysate,Lane3: EA.hy926 cell lysate,Lane4: HUH7 cell lysate;Primary Ab: 1.5µg/ml Mouse Anti-Human TFPI AntibodySecond Ab: 0.2µg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Application Notes WB: 0.01-2µg/mL
Additional Information
Form Liquid
Storage Instructions Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Storage Buffer 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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