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Monoclonal Antibody to Kisspeptin 1 (KISS1)
Catalog Number:OM699677
Human
WB;IHC
OM699677
Discount Price
OM699677-100ul
100ul
Product Profile
Product Name Monoclonal Antibody to Kisspeptin 1 (KISS1)
Antibody Type Primary Antibodies
Immunogen RPC559Hu01-Recombinant Kisspeptin 1 (KISS1)
Key Feature
Clonality Monoclonal
Isotype IgG1 Kappa
Host Species Mouse
Tested Applications WBIHC
WB: 0.01-2µg/mL
IHC: 5-20µg/mL
ICC/IF: 5-20µg/mL
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A/G
Target Information
Gene Symbol KISS1
Gene Synonyms HH13,KiSS-1
Gene Full Name KiSS-1 metastasis suppressor
Gene Summary This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH neurons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Jun 2022]
Alternative Names Metastin
KiSS-1 Metastasis-Suppressor
Application

IHC

Vector Red staining on IHC-P,Samples: Human Placenta Tissue,Primary Ab: 10µg/ml Mouse Anti-Human KISS1 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Monoclonal Antibody

WB

Figure. Western Blot,Sample: Recombinant KISS1, Human.
Application Notes WB: 0.01-2µg/mL
IHC: 5-20µg/mL
ICC/IF: 5-20µg/mL
Additional Information
Form Liquid
Storage Instructions Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Storage Buffer 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
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