This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Alternative Names
PRL SFTPA PSAP PSPA SFTP SPA COLEC4 PSP-A SFTP1 SFTPA1B SP-A1 Collectin-4 Alveolar proteinosis protein 35 kDa pulmonary surfactant-associated protein Surfactant Associated Protein A
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.