Monoclonal Antibody to Natriuretic Peptide Precursor B (NPPB)
Antibody Type
Primary Antibodies
Immunogen
RPA503Mu01-Recombinant Natriuretic Peptide Precursor B (NPPB)
Key Feature
Clonality
Monoclonal
Isotype
IgG1Kappa
Host Species
Mouse
Tested Applications
IHC
IHC: 5-30µg/mL
Species Reactivity
Mouse
Concentration
1mg/ml
Purification
Protein A/G
Target Information
Gene Symbol
Nppb
Gene Synonyms
BNF,BNP,Iso-ANP
Gene Full Name
natriuretic peptide type B
Gene Summary
This gene encodes a secreted protein that belongs to the family of natriuretic peptides. Its precursor protein is processed to generate the active mature peptide. The mature peptide is a cardiac hormone that plays a role in ventricular remodeling as well as blood pressure regulation. Mice lacking this gene exhibit cardiac fibrosis. In humans this gene is associated with congestive heart failure, low bone-mineral density and postmenopausal osteoporosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Application
IHC
DAB staining on IHC-P,Sample: Mouse Cardiac Muscle Tissue Primary Ab: 30µg/ml Mouse Anti-Mouse NPPB Antibody Control: Used PBS instead of primary antibody Second Ab: 2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
Application Notes
IHC: 5-30µg/mL
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.