| Product Name | Human LRP8 Recombinant protein |
|---|---|
| Species Reactivity | Human |
| Gene Symbol | LRP8 |
| Gene Synonyms | MCI1 LRP-8 APOER2 HSZ75190 |
| Gene Full Name | LDL receptor related protein 8 |
| Gene Summary | This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
