This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Alternative Names
antigen identified by monoclonal antibody 1D8 antigenic surface determinant protein OA3 CD47 antigen CD47 antigen (Rh-related antigen integrin-associated signal transducer) CD47 glycoprotein IAP integrin associated protein integrin-associated protein integrin-associated signal transducer Rh-related antigen sCD47 soluble CD 47 soluble CD47