IL8, CXCL8, IL-8(9-77), IL8/NAP1 form VI;GCP/IL-8 protein III
Key Feature
Clonality
Monoclonal
Clone Number
EP1117Y
Host Species
Rabbit
Tested Applications
WB
WB:1:50000~100000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CXCL8
Alternative Names
IL8 CXCL8 IL-8(9-77) IL8/NAP1 form VI GCP/IL-8 protein III
Molecular Weight(MW)
11098 Da
Function
IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively
Tissue Specificity
A synthetic peptide corresponding to residues in human IL-8 was used as an immunogen.