Immunohistochemistry
Immunohistochemistry with Testis tissue at an antibody concentration of 5ug/ml using anti-PHOX2A antibodyWestern blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate| Product Name | Rabbit anti-PHOX2A polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A |
| Immunogen | The immunogen for anti-PHOX2A antibody: synthetic peptide directed towards the N terminal of human PHOX2A |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogPigRabbitRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PHOX2A |
|---|---|
| Gene Synonyms | ARIX CFEOM2 FEOM2 MGC52227 NCAM2 PMX2A |
| Gene Full Name | Paired-like homeobox 2a |
| Gene Summary | PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
| Alternative Names | ARIX CFEOM2 FEOM2 MGC52227 NCAM2 PMX2A |
| Molecular Weight(MW) | 30kDa |
| Sequence | 284 amino acids |
Immunohistochemistry
Immunohistochemistry with Testis tissue at an antibody concentration of 5ug/ml using anti-PHOX2A antibody
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
