Application
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.Application
Antibody used in IHC on Human Testis at 5 ug/ml.| Product Name | PHOX2A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PHOX2A, ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A |
| Product description | PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Imai, S., (2008) Acta Med. Okayama 62 (1), 45-53. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHOX2A. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| PHOX2A antibody can be used for detection of PHOX2A by ELISA at 1:1562500. PHOX2A antibody can be used for detection of PHOX2A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PHOX2A |
|---|---|
| Alternative Names | PHOX2A ARIX CFEOM2 FEOM2 MGC52227 NCAM2 PMX2A |
| Molecular Weight(MW) | 30 kDa |
Application
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.
Application
Antibody used in IHC on Human Testis at 5 ug/ml.| Positive Control | 1) 721_B Cell Lysate |
|---|---|
| Application Notes | PHOX2A antibody can be used for detection of PHOX2A by ELISA at 1:1562500. PHOX2A antibody can be used for detection of PHOX2A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store PHOX2A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
