Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Muscle| Product Name | Rabbit anti-ZFPM1 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FOG, FOG1, ZNF408, ZNF89A |
| Immunogen | The immunogen for anti-ZFPM1 antibody: synthetic peptide directed towards the middle region of human ZFPM1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Bovine |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZFPM1 |
|---|---|
| Gene Synonyms | FOG FOG1 ZNF408 ZNF89A |
| Gene Full Name | Zinc finger protein, multitype 1 |
| Gene Summary | ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2. |
| Alternative Names | FOG FOG1 ZNF408 ZNF89A |
| Molecular Weight(MW) | 105kDa |
| Sequence | 1006 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Muscle| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
