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Rabbit anti-HNF1B polyclonal antibody - N-terminal region
Catalog Number:OM105723
OM105723
Discount Price
OM105723-100ul
1~2 Week
100ul
OM105723-50ul
50ul
OM105723-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-HNF1B polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
Immunogen The immunogen for anti-HNF1B antibody: synthetic peptide directed towards the N terminal of human HNF1B
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol HNF1B
Gene Synonyms FJHN
HNF1beta
HNF2
LFB3
MODY5
TCF2
VHNF1
HPC11
LF-B3
Gene Full Name HNF1 homeobox B
Gene Summary Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1; depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.
Alternative Names FJHN
HNF1beta
HNF2
LFB3
MODY5
TCF2
VHNF1
HPC11
LF-B3
Molecular Weight(MW) 45kDa
Sequence 399 amino acids
Database Links
Entrez Gene 6928
SwissProt ID P35680
Protein Accession NP_006472
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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