SMRT TRAC CTG26 SMRTE TRAC1 N-CoR2 TNRC14 TRAC-1 SMAP270 SMRTE-tau
Gene Full Name
Nuclear receptor corepressor 2
Gene Summary
NCOR2 forms a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid (TR) and the retinoid acid receptors (RAR) in the absence of ligand, and may stabilize their interaction with TFIIB. NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Alternative Names
SMRT TRAC CTG26 SMRTE TRAC1 N-CoR2 TNRC14 TRAC-1 SMAP270 SMRTE-tau