Western blot
Titration: 5 ug/ml| Product Name | AIRE antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-AIRE antibody: synthetic peptide directed towards the N terminal of human AIRE |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Horse,Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | AIRE |
|---|---|
| Gene Synonyms | APS1 APSI PGA1 AIRE1 APECED |
| Gene Full Name | Autoimmune regulator |
| Gene Summary | AIRE is a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). |
| Alternative Names | APS1 APSI PGA1 AIRE1 APECED |
| Molecular Weight(MW) | 58kDa |
| Sequence | 545 amino acids |
Western blot
Titration: 5 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
