Western blot
1.25ug/ml| Product Name | PTK2B antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-PTK2B antibody: synthetic peptide directed towards the C terminal of human PTK2B |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Horse,Human,Mouse,Pig,Rabbit |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PTK2B |
|---|---|
| Gene Synonyms | PKB PTK CAKB FAK2 PYK2 CADTK FADK2 RAFTK |
| Gene Full Name | PTK2B protein tyrosine kinase 2 beta |
| Gene Summary | PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. |
| Alternative Names | PKB PTK CAKB FAK2 PYK2 CADTK FADK2 RAFTK |
| Molecular Weight(MW) | 116kDa |
| Sequence | 1009 amino acids |
Western blot
1.25ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
