Immunohistochemical
ThymusWestern blot
0.2-1 ug/ml| Product Name | BCL11B antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-BCL11B antibody: synthetic peptide directed towards the middle region of human BCL11B |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB,IHC |
| Species Reactivity | Bovine,Dog,Guinea Pig,Human,Mouse,Pig,Rabbit,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BCL11B |
|---|---|
| Gene Synonyms | CTIP-2 CTIP2 RIT1 hRIT1-alpha ZNF856B |
| Gene Full Name | B-cell CLL/lymphoma 11B (zinc finger protein) |
| Gene Summary | BCL11B is the tumor-suppressor protein involved in T-cell lymphomas. BCL11B may function on the P53-signaling pathway. BCL11B may be a key regulator of both differentiation and survival during thymocyte development. BCL11B repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. |
| Alternative Names | CTIP-2 CTIP2 RIT1 hRIT1-alpha ZNF856B |
| Molecular Weight(MW) | 88kDa |
| Sequence | 823 amino acids |
Immunohistochemical
Thymus
Western blot
0.2-1 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
