Western blot
0.2-1 ug/ml| Product Name | EPC1 antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-EPC1 antibody: synthetic peptide directed towards the middle region of human EPC1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Pig,Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EPC1 |
|---|---|
| Gene Synonyms | DKFZp781P2312 Epl1 |
| Gene Full Name | Enhancer of polycomb homolog 1 (Drosophila) |
| Gene Summary | EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. |
| Alternative Names | DKFZp781P2312 Epl1 |
| Molecular Weight(MW) | 93kDa |
| Sequence | 836 amino acids |
Western blot
0.2-1 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
