Western blot
0.5ug/mlPositive Control: HepG2 cell lysate| Product Name | Rabbit anti-ATP7A polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MK, MNK, DSMAX, SMAX3 |
| Immunogen | The immunogen for anti-ATP7A antibody: synthetic peptide directed towards the N terminal of human ATP7A |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ATP7A |
|---|---|
| Gene Synonyms | MK MNK DSMAX SMAX3 |
| Gene Full Name | ATPase, Cu++ transporting, alpha polypeptide |
| Gene Summary | The ATP7A gene encodes the Menkes copper-translocating P-type ATPase, a ubiquitous protein that regulates the absorption of copper in the gastrointestinal tract. Inside cells, this protein has a dual function: it delivers copper to cuproenzymes in the Golgi compartment and effluxes excess copper. The trafficking mechanism and catalytic activity combine to facilitate absorption and intercellular transport of copper. Menkes disease, a systemic copper deficiency disorder, is caused by mutations in the ATP7A gene. |
| Alternative Names | MK MNK DSMAX SMAX3 |
| Molecular Weight(MW) | 30kDa |
| Sequence | 274aa amino acids |
Western blot
0.5ug/mlPositive Control: HepG2 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
