Immunohistochemistry
Immunohistochemistry with Lung tissue at an antibody concentration of 5ug/ml using anti-Pthlh antibodyWestern blot
1 ug/ml| Product Name | Pthlh antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-Pthlh antibody: synthetic peptide corresponding to a region of Mouse |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC,WB |
| Species Reactivity | Guinea Pig,Horse,Human,Mouse,Pig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Pthlh |
|---|---|
| Gene Synonyms | PTH-like Pthrp |
| Gene Full Name | Parathyroid hormone-like peptide |
| Gene Summary | Pthlh is a neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. It regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is required for skeletal homeostasis. It promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. It upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath. |
| Alternative Names | PTH-like Pthrp |
| Molecular Weight(MW) | 16kDa |
| Sequence | 175 amino acids |
Immunohistochemistry
Immunohistochemistry with Lung tissue at an antibody concentration of 5ug/ml using anti-Pthlh antibody
Western blot
1 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
