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Trp63 antibody - middle region

Catalog Number:OM106627
OM106627
Discount Price
OM106627-100ul
1~2 Week
100ul
OM106627-50ul
50ul
OM106627-20ul
20ul
1~2 Week
Product Profile
Product Name Trp63 antibody - middle region
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Guinea Pig,Mouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol Trp63
Gene Synonyms AI462811
Ket
MGC115972
P51/P63
P63
P73l
Tp63
Trp53rp1
Gene Full Name Transformation related protein 63
Gene Summary This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium.
Alternative Names AI462811
Ket
MGC115972
P51/P63
P63
P73l
Tp63
Trp53rp1
Molecular Weight(MW) 50kDa
Sequence 461 amino acids
Database Links
Entrez Gene 22061
SwissProt ID Q9WV31
Protein Accession NP_061260
Application

Western blot

Titration: 1.0 ug/ml
Positive Control: Mouse heart
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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