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Rabbit anti-PTGER3 polyclonal antibody - middle region

Catalog Number:OM106643
OM106643
Discount Price
OM106643-100ul
1~2 Week
100ul
OM106643-50ul
50ul
OM106643-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-PTGER3 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, MGC141828, MGC141829, MGC27302, PGE2-R
Immunogen The immunogen for anti-PTGER3 antibody: synthetic peptide directed towards the middle region of human PTGER3
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity HorseHuman
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PTGER3
Gene Synonyms EP3
EP3-I
EP3-II
EP3-III
EP3-IV
EP3e
MGC141828
MGC141829
MGC27302
PGE2-R
Gene Full Name Prostaglandin E receptor 3 (subtype EP3)
Gene Summary PTGER3 is the receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple alternatively spliced transcript variants encoding eight distinct isoforms have been reported.
Alternative Names EP3
EP3-I
EP3-II
EP3-III
EP3-IV
EP3e
MGC141828
MGC141829
MGC27302
PGE2-R
Molecular Weight(MW) 43kDa
Sequence 390 amino acids
Database Links
Entrez Gene 5733
SwissProt ID P43115
Protein Accession NP_942012
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human Stomach
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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