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Rabbit anti-XRCC4 polyclonal antibody - middle region

Catalog Number:OM106675
OM106675
Discount Price
OM106675-100ul
1~2 Week
100ul
OM106675-50ul
50ul
OM106675-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-XRCC4 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-XRCC4 antibody: synthetic peptide directed towards the middle region of human XRCC4
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRabbitRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol XRCC4
Gene Synonyms -
Gene Full Name X-ray repair complementing defective repair in Chinese hamster cells 4
Gene Summary XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes.The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. This gene contains 8 exons, and alternative transcription initiation and alternative splicing generates several transcript variants.
Molecular Weight(MW) 38kDa
Sequence 336 amino acids
Database Links
Entrez Gene 7518
SwissProt ID Q13426
Protein Accession NP_071801
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:2500Positive Control: Human Placenta
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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