Application
Western blot analysis in A549 cell line lysates (35ug/lane).| Product Name | XRCC4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DNA repair protein XRCC4, X-ray repair cross-complementing protein 4, XRCC4 |
| Product description | The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq].1) Gomes, B.C., et al. Oncol. Rep. 24(4):1079-1085(2010) |
| Immunogen | This XRCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human XRCC4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | XRCC4 |
|---|---|
| Alternative Names | DNA repair protein XRCC4 X-ray repair cross-complementing protein 4 XRCC4 |
| Molecular Weight(MW) | 38 kDa |
Application
Western blot analysis in A549 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
