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COPS2 antibody - N-terminal region

Catalog Number:OM106712
OM106712
Discount Price
OM106712-100ul
1~2 Week
100ul
OM106712-50ul
50ul
OM106712-20ul
20ul
1~2 Week
Product Profile
Product Name COPS2 antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-COPS2 antibody: synthetic peptide directed towards the N terminal of human COPS2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Pig,Rabbit,Rat,Zebra Fish
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol COPS2
Gene Synonyms COPS2
Gene Full Name COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)
Gene Summary COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/Ion ChannelSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
Alternative Names ALIEN
CSN2
SGN2
TRIP15
Molecular Weight(MW) 52kDa
Sequence 443 amino acids
Database Links
Entrez Gene 9318
SwissProt ID P61201
Protein Accession NP_004227
Application

Application

Sample Type: 1. Markers
2. B8 mouse fibroblast cells, extraction only
3. Human total cell extract
4. Human blood cells, partially purified
5. Pombe, extraction only
Primary Dilution: 1:200
Secondary Anitbody: HRP conjugated anti-rabbit
Image Submitted By: Dr. Elah Pick
University of Haifa at Oranim 

Application

WB Suggested Anti-COPS2 Antibody Titration: 0.5ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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