Application
WB Suggested Anti-CBX3 Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysateCBX3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cellsApplication
Human Lung| Product Name | Rabbit anti-CBX3 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HECH, HP1-GAMMA, HP1Hs-gamma |
| Immunogen | The immunogen for anti-CBX3 antibody: synthetic peptide directed towards the middle region of human CBX3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMousePigRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CBX3 |
|---|---|
| Gene Synonyms | CBX3 |
| Gene Full Name | Chromobox homolog 3 |
| Gene Summary | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. CBX3 binds DNA and is a component of heterochromatin. CBX3 also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of CBX3 may explain the association of heterochromatin with the inner nuclear membrane.At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene. |
| Alternative Names | HECH HP1-GAMMA HP1Hs-gamma |
| Molecular Weight(MW) | 21kDa |
| Sequence | 183 amino acids |
Application
WB Suggested Anti-CBX3 Antibody Titration: 1.25ug/mlPositive Control: Jurkat cell lysateCBX3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
Application
Human Lung| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
