Application
Antibody used in IHC on Human Lung.Application
Antibody used in WB on Human Jurkat cells at 1.25 ug/ml.| Product Name | CBX3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CBX3, HECH, HP1-GAMMA, HP1Hs-gamma |
| Product description | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. CBX3 binds DNA and is a component of heterochromatin. CBX3 also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of CBX3 may explain the association of heterochromatin with the inner nuclear membrane.At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.1) Scherer, S.W., (2003) Science 300 (5620), 767-772. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBX3. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| CBX3 antibody can be used for detection of CBX3 by ELISA at 1:62500. CBX3 antibody can be used for detection of CBX3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
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| Species Reactivity | DogHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CBX3 |
|---|---|
| Alternative Names | CBX3 HECH HP1-GAMMA HP1Hs-gamma |
| Molecular Weight(MW) | 21 kDa, 21 kDa, 21 kDa |
Application
Antibody used in IHC on Human Lung.
Application
Antibody used in WB on Human Jurkat cells at 1.25 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | CBX3 antibody can be used for detection of CBX3 by ELISA at 1:62500. CBX3 antibody can be used for detection of CBX3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CBX3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
