Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HT1080 cell lysate| Product Name | Rabbit anti-DMTF1 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DMP1, DMTF, FLJ41265, hDMP1 |
| Immunogen | The immunogen for anti-DMTF1 antibody: synthetic peptide directed towards the middle region of human DMTF1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DMTF1 |
|---|---|
| Gene Synonyms | DMP1 DMTF FLJ41265 hDMP1 |
| Gene Full Name | Cyclin D binding myb-like transcription factor 1 |
| Gene Summary | DMTF1 is a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. DMTF1 is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of DMTF1 is regulated by binding of D-cyclins. The gene encoding DMTF1 is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. |
| Alternative Names | DMP1 DMTF FLJ41265 hDMP1 |
| Molecular Weight(MW) | 84kDa |
| Sequence | 760 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HT1080 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
