Western blot
KCNN3 antibody - C-terminal region validated by WB using Mouse kidney , Whole brain lysate at 2 ug/ml.Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Daudi cell lysate| Product Name | Rabbit anti-KCNN3 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SK3, hSK3, SKCA3, KCa2.3 |
| Immunogen | The immunogen for anti-KCNN3 antibody: synthetic peptide directed towards the C terminal of human KCNN3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KCNN3 |
|---|---|
| Gene Synonyms | SK3 hSK3 SKCA3 KCa2.3 |
| Gene Full Name | Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 |
| Gene Summary | Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. |
| Alternative Names | SK3 hSK3 SKCA3 KCa2.3 |
| Molecular Weight(MW) | 81kDa |
| Sequence | 736 amino acids |
Western blot
KCNN3 antibody - C-terminal region validated by WB using Mouse kidney , Whole brain lysate at 2 ug/ml.
Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Daudi cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
