Western blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: 293T Antibody Dilution: 1.0ug/mlWestern blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: Hela Antibody Dilution: 1.0ug/mlWestern blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: 721_B Antibody Dilution: 1.0ug/mlWestern blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: MCF7 Antibody Dilution: 1.0ug/mlWestern blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: Jurkat Antibody Dilution: 1.0ug/mlWestern blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: HepG2 Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-TRPM4 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ20041, TRPM4B, PFHB1B |
| Immunogen | The immunogen for anti-TRPM4 antibody: synthetic peptide directed towards the N terminal of human TRPM4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TRPM4 |
|---|---|
| Gene Synonyms | FLJ20041 TRPM4B PFHB1B |
| Gene Full Name | Transient receptor potential cation channel, subfamily M, member 4 |
| Gene Summary | TRPM4 is a calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca2+, it is impermeable to it. TRPM4 mediates transport of monovalent cations (Na+ > K+ > Cs+ > Li+), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca2+ oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. TRPM4 is involved in myogenic constriction of cerebral arteries. It controls insulin secretion in pancreatic beta-cells. TRPM4 may also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca2+ overload. |
| Alternative Names | FLJ20041 TRPM4B PFHB1B |
| Molecular Weight(MW) | 134kDa |
| Sequence | 1214 amino acids |
Western blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: 293T Antibody Dilution: 1.0ug/ml
Western blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: Hela Antibody Dilution: 1.0ug/ml
Western blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: 721_B Antibody Dilution: 1.0ug/ml
Western blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: MCF7 Antibody Dilution: 1.0ug/ml
Western blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: Jurkat Antibody Dilution: 1.0ug/ml
Western blot
Host: Rabbit Target Name: TRPM4 Sample Tissue: HepG2 Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
