The protein encoded by this gene is a calcium-activated
nonselective ion channel that mediates transport of monovalent
cations across membranes, thereby depolarizing the membrane. The
activity of the encoded protein increases with increasing
intracellular calcium concentration, but this channel does not
transport calcium. Two transcript variants encoding different
isoforms have been found for this gene.1) Liu, H., et al. Circ Cardiovasc Genet 3(4):374-385(2010)
Immunogen
This TRPM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1121-1149 amino acids from the C-terminal region of human TRPM4.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.