| Gene Symbol |
KCNMB3
|
| Gene Synonyms |
KCNMB2 KCNMBL HBETA3 BKBETA3 SLOBETA3 |
| Gene Full Name |
Potassium large conductance calcium-activated channel, subfamily M beta member 3 |
| Gene Summary |
KCNMB3 is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for KCNMB3.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for this gene. |
| Alternative Names |
KCNMB2 KCNMBL HBETA3 BKBETA3 SLOBETA3 |
| Molecular Weight(MW) |
31kDa |
| Sequence |
277 amino acids |