Calcium activated K+ channels are comprised of two subunits: a large pore forming alpha subunit and a smaller modulatory beta subunit. Four splice variants of Kcnmb3 (beta 3) have been isolated that vary at the N-terminus and in their tissue distribution. Coexpression with BKalpha of all beta 3 splice variants resulted in only partial inactivation of the channel current. In addition, unlike the beta 1 and beta 2 subunits, none of the beta 3 subunits increased channel sensitivity to calcium or voltage.
Immunogen
KCNMB3 antibody was raised against a peptide located near the internal domain of KCNMB3 (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHC
KCNMB3 antibody can be used in immunohistochemistry starting at 10 μg/mL, immunofluorescence, and flow cytometry.